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Histopathological presentation of ovarian lesions in Indian women: An observational study

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Dr. Atul Kumar Pandey, Dr. Chakresh Jain, Dr. Sonu Kumar Batham, Dr. Parul Nema
» doi: 10.48047/ecb/2023.12.Si6.054


An age-associated escalation in the prevalence of ovarian cancer is reported by majority of Indian population-based cancer registries. Due to the presence of totipotent gametocytes and multipotent Mesenchymal tissues, the ovary is susceptible to the development of various tumor types. The current investigation endeavored to examine the histopathological characteristics of ovarian lesions in Indian female patients. Materials and Methods: A prospective observational investigation was conducted on ovarian samples that had undergone surgical resection and were referred to the Pathology department of tertiary care teaching hospital over a span of two years. 163 cases of ovarian cancer were included. Standardized histopathological protocols were employed to examine the specimen. Results: On gross examination, the vast majority of non-neoplastic specimens displayed unremarkable findings. Upon microscopic examination of non-neoplastic cases, it was observed that a majority of the cases exhibited follicular cyst, with corpus luteum cyst presenting as the second most frequent. Majority of neoplastic specimens displayed a cystic external surface upon gross examination. The surface epithelial tumor was found to be the most prevalent histologic subtype among the neoplastic cases. The prevalent histologic subtype among surface epithelial tumors was benign simple serous cystadenoma. Conclusion: The predominant non-neoplastic ovarian lesion in Indian women is the follicular cyst, while the most frequently occurring neoplastic lesion is the benign simple serous cystadenoma, which is a type of surface epithelial tumor.

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