The COVID-19 outbreak poses a significant threat to the physical and mental health of people all around the world. Every community on earth is being adversely affected by the pandemic. The effect of COVID-19 on psychological health, particularly among “Health-Care Workers (HCWs)”, has not been adequately addressed as a result of pandemic fatigue, in part because HCWs are more fearful of contracting the disease, dying from it, experiencing increased work-related stress, and being over-saturated with news on social media and other platforms. The current survey analyses the anxiety and the level of knowledge among the HCWs in the current scenario of the COVID-19. Material and methods: The knowledge and anxiety levels of 212 HCWs at a north Indian tertiary care hospital about the COVID-19 were assessed by an online survey utilising a specially created questionnaire. The questionnaire was constructed based on the previous studies that analysed the same among the various HCWs. All of the HCWs who were at the center received the questionnaire and an informed consent in order to evaluate their understanding of and anxiety about COVID-19. The observations made were presented as percentages.