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Hba1c in the Al-Najaf governorate and the impact of marital status and depression

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Sadeq Mohammad Jaafar almosawi, Suaad Mohammad Joda AL-Hadrawy
» doi: 10.48047/ecb/2023.12.si6.168


HbA1c , or glycated hemoglobin, has become the gold standard for evaluating glycemic management in people with diabetes [1]. Diabetes has been diagnosed for many years using random glucose or fasting glucose as the glucose standards. Although HbA1c was initially used in 2010 as a diagnostic criterion for diabetes at a cutoff of 6.5%, pre-diabetes between 5.7% and 6.4%, and normal 5.7% [2]. Haemoglobin, which is found in red blood cells, is a protein that carries oxygen and contains iron. The typical form of haemoglobin found in adults, called HbA, consists of a haem component and two chains of globin, known as the α and β chains (α2β2). making up just about 97% of adult haemoglobin [3]. Approximately 6% of HbA is glycated; the majority of this is HbA1c (5%), with tiny amounts of HbA1a and HbA1b (1% each) [4]. Glycation, a nonenzymatic process that results in the covalent attachment of glucose to the N-terminal valine of the hemoglobin -chain, is what causes HbA1c [5]. Marriage can improve a person's general health, including their ability to control their blood sugar levels, as it serves as a social and emotional support system. A study found that married people had significantly lower HbA1c levels than single people [6]. Another study looked at the association between HbA1c levels and the quality of marriage. Even after adjusting for age, sex, the length of the diabetes, medication use, and other health characteristics, the study revealed that better marital satisfaction was associated with lower HbA1c levels in both couples. The researchers hypothesized that healthy relationships could encourage greater self-care and wellness practices, which would improve glycemic management [7].

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