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ISSN 2063-5346
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FORMULATION, OPTIMIZATION, AND EVALUATION OF TRANSDERMAL PATCHES OF ECLIPA ALBA LEAF EXTRACT

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Gireesh Tripathi, Narendra Lariya
» doi: 10.31838/ecb/2023.12.sa1.236

Abstract

The purpose of this research was to develop a matrix-type transdermal therapeutic system containing Eclipa Alba leaf extract with different ratios of hydrophilic polymeric systems by the solvent evaporation technique by using 30% (w/w) of PEG 400 LR to the dry polymer weight, incorporated as a plasticizer. A methanolic extract of Eclipa Alba was produced and analyzed using the Maceration process. Different concentrations of oleic acid and isopropyl myristate were used to enhance the transdermal permeation of Eclipa Alba leaf extract. The physicochemical compatibility of the drug and the polymers studied by infrared spectroscopy suggested the absence of any incompatibility.

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