The purpose of this article review was to study hydrogel acne patch formulation. Acne causes several types of lesions, like whiteheads, blackheads, pustules, pimples, and nodules. Acne affects people of all ages, but it is most common in teenagers and younger adults. Acne treatment products such as creams, face washes, and others are available on the market. However, the patches outperform acne creams and face washes due to two significant advantages. To help prevent the spread of bacteria and dirt, the sticker first acts as a barrier by forbidding touching or picking at the injured area. Second, the hydrogel patch absorbs the pimple's inflammatory pus while also keeping the area moist. These benefits encourage the creation of cutting-edge transdermal acne patches. This transdermal acne patch contains salicylic acid as an active pharmaceutical ingredient. Bacteria that clog pores and cause inflammation are removed.