The purpose of this research was to develop fast disintegrating tablets of Diclofenac Potassium containing natural super disintegrant from Plantago ovata(family: Plantaginaceae). The mucilage was extracted from seeds of Plantago ovataand used to develop the fast disintegrating tablet of Diclofenac Potassium. The disintegration property of mucilage powder in FDTs was compared with widely used superdisintegrants like Sodium Starch Glycolate (SSG), and Ac-Di-Sol.The prepared FDTs were evaluated for uniformity of weight, hardness, thickness, friability,anddisintegration time, In-vitro dissolution. From the study, it was concluded that Diclofenac Potassium tablet containingplantago ovataseed mucilage powder shows disintegration time 18 sec which was less than SSG and Ac-Di-Sol