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ISSN 2063-5346
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EXTRAGENITAL PATHOLOGY OF THE MOTHER AND MORPHOLOGICAL FEATURES OF THE DEVELOPMENT OF THE THYMUS IN THE PERIOD OF EARLY POSTNATAL ONTOGENESIS

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Khasanov Bakhtiyor Burtkhanovich, Azimova Sabokhat Bakhodurovna
» doi: 10.48047/ecb/2023.12.8.673

Abstract

The influence of chronic toxic hepatitis (CTH) of the mother on the development of the offspring thymus in the dynamics of early postnatal ontogenesis was studied. We used 120 female outbred rats weighing 110-120 g, and 120 male rat pups on days 1, 3, 7, 15, 21 and 30 after birth. Along with researches of changes in the thymus of the offspring, it was found that females with CTG had impaired fertility, only 84% of the females were pregnant after mating, only 64% of the pregnancy ended in childbirth, 8% miscarriages, and the rest had mortality during pregnancy, after childbirth rat pups showed up to 39.6% increase in infant mortality

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