Clitoria ternatea commonly known as butterpea belongs to the family Fabaceae.The study of toxicology is to determine the poisonous,harmful and adverse effect produced by drugs and other chemicals constituents isolated from plants sources which increases the chances of mortality or issues in general health.The present study has been pioneered to study the adverse or hazardous effect of hydroalcoholic extract of Clitoria ternatea and to ensure the safety of albino wister mice (180-200g) as per (OECD ) OrganizationforEconomic CooperationandDevelopment guidelines 423.In the present study ,the oral dose of(50,100,250mg/kg) were administerd for four group of animals in single dose and observed for 14 days to understand the general behaviour,adverse effects and moratlaity were monitored. In acute toxicity, all treated groups revealed neither mortality nor any significant changes were observed. The result indicates that the oral administration of plant hydroalcoholic extract of Clitoria ternatea did not produce any significant toxic effect in albino rats. Hence, the extract can be utilized safely for therapeutic use in pharmaceutical formulations.