Epipremnum aureum and Morus alba leaves were screened for phytochemical constituents. Phytochemical analysis of the extract revealed that the wound healing activity by wound excision and incision methods. The plant material is due to the presence of active constituents like tannins or flavonoids. Epipremnum aureum is used in disease related to anti-bacterial , anti-termite , anti-oxidant , anti-malarial , anti-cancerous , anti-tuberculosis , anti-arthritis and wound healing activities and also Morus alba is used to treat disorders like dizziness , insomnia , premature aging , atherosclerosis , liver ,kidney disorders and inflammation. In the present study contains Epipremnum aureum and Morus alba leaves samples were obtained by using Maceration (softening) Process. Phytochemical studies revealed that tannins and flavonoids are present in the sample