AIM The aim of this original research study is to evaluate the efficacy of Platelet-Rich Plasma (PRP) in the regeneration process of non-vital immature permanent teeth. OBJECTIVE Assess the impact of PRP treatment on root development in non-vital immature permanent teeth.Evaluate the ability of PRP to promote apex closure in non-vital immature permanent teeth. Investigate the effect of PRP on periapical healing in non-vital immature permanent teeth. Analyze patient-reported outcomes, including pain levels and satisfaction, following PRP treatment.