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ISSN 2063-5346
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EVALUATING THE INCIDENCE OF PREDIABETES IN PCOS WOMEN WITH DEPRESSIVE SYMPTOMS: A CROSS SECTIONAL STUDY

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Gopikanath.S 1 , Farheena Thasneem1 , Haripriya.B1 , Janavi.M1 , Dr. K. Karthickeyan*
» doi: 10.31838/ecb/2023.12.s1-B.463

Abstract

INTRODUCTION: Polycystic ovary syndrome is one of the most common endocrine disorders in women of reproductive age (15- 49) which affects the QOL and can worsen with the presence of anxiety and depression particularly due to obesity or sudden weight loss, excessive body hairs(hirsutism), fertility issues, and changes in the physical appearances. Longer exposure of depression leads to the onset of type 2 diabetes mellitus while a considerable period of exposure of depression in women with PCOS leads to the onset of prediabetes due to the bidirectional association between depression and diabetes. OBJECTIVES: The research aims to determine the potential incidence of Pre diabetes associated with depression in PCOS women of age 18-30. To provide appropriate lifestyle modification through counselling to manage the condition for patient who have high stress and depressive score. To improve quality of life of PCOS women. METHOD: The study includes 37 patients aged 18-30 years, who are already diagnosed with PCOD and have depressive symptoms, which is assessed using a standard scale called Beck’s depression scale which evaluates mild mood disturbance, borderline clinical depression and moderate, severe, extreme depression. Their stress levels are also assessed using perceived stress scale. All 37 patients are then monitored for their fasting blood sugar, Hba1c, OGTT (Oral Glucose Tolerance Test) to evaluate the occurrence of prediabetes and then compare it with the level of depression of the patient. RESULT: A total of 37 patients were included in the study. The majority of the patient were between the age group 18- 30; about 40.5% have reported severe depression and more than 50% of the patients had hormonal imbalances, which contributed as major risk factors of PCO. More than 54.5% patient had risk factors of pre-diabetes. Beck’s Depression Scale revealed that all the patients had risk factors of Depression. CONCLUSION: Based on the findings of our research, we concluded that there is a strong connection between the rise in HbA1C level and depression, suggesting a possible link between rising depressive symptoms and prediabetes in PCOS patients. Diabetes mellitus and depression incidence would be significantly reduced by reducing the risk factors of PCOS patients, such as weight gain, acne, hirsutism, and scalp hair loss with the presence of depressed symptoms. The quality of life for patients with PCOS would be significantly improved by an early identification of diabetes mellitus and depression. Studies are also needed to determine the incidence of PCOS risk factors in a wider population.

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