Health Information Exchange (HIE) systems have emerged as a promising solution to improve care coordination among healthcare providers. This review article aims to critically evaluate the effectiveness of HIE systems in enhancing care coordination. The review will analyze existing literature on the impact of HIE systems on care coordination, focusing on key aspects such as communication among healthcare providers, continuity of care, patient outcomes, and overall healthcare quality. Various studies assessing the implementation and outcomes of HIE systems will be reviewed to provide a comprehensive understanding of their effectiveness in improving care coordination. Additionally, challenges and barriers to successful HIE implementation will be discussed, along with potential strategies to address these issues. The review will also highlight gaps in current research and suggest directions for future studies to further explore the role of HIE systems in care coordination.