This study investigated the roles of serum BNP, NGAL, and UPAR in patients with (pre) and (post) catheter myocardial infarction (MI) and compared them with healthy subjects. The included MI patients (n = 50) who underwent catheterization and were admitted to the Cardiac Intensive Care Section of Al-Sadr Teaching Hospital in Al-Najaf Governorate/Iraq had their blood drawn. The patients were divided into two subgroups(pre)and (post) angioplasty. Serum levels of BNP, NGAL, and UPAR were measured in all patients before and after angioplasty. The result of this study showed a significant (p < 0.05) decrease in serum BNP levels in the (pre) patients of MI group compared to the control group (n=25), while serum NAGL and UPAR levels did not show a significant difference (p > 0.05) in the patient's MI group (before) and (after) compared to the control group. In conclusion, serum levels of BNP, NGAL, and UPAR have no potential predictive value in MI patients undergoing catheterization.