In this study, 120 middle-aged lung-affected patients were selected at random, observing random sampling method, screened, and further reduced to 40 with their Chest X-ray, from a fireworks factory at Sivakasi, Tamil Nadu, between 35 to 50 years of age. Women were grouped into an experimental and control group of 20 each. The hypothesis was fixed that there would be a positive impact on Eosinophils among middle-aged women suffering from pneumoconiosis due to yogic practices. The Experimental Group underwent therapy for 12 weeks one hour each day. The control group was allowed to lead a normal life. The data collected from the groups were statistically analyzed by Analysis of Variance (ANOVA). The result of the study showed that Eosinophils were decreased significantly due to regular Yogic practices. The hypothesis was accepted at a 0.05 level of confidence.