The present random group experimental study was designed to find out the effect of Yogic practices on Selected Biochemical variable among middle-aged hypertensive women. To achieve the purpose of the study, 40 hypertensive women were selected from Chennai city randomly by using a random group sampling design. They were in the age group of 40-50 years. They were randomly divided into two groups and each group contained twenty subjects. The Experimental Group was trained in Yogic practices and the Control Group was kept without any intervention. It was hypothesized that the Yogic practices reduced Blood Sugar, among middle-aged hypertensive women. Thus, the hypothesis was accepted at 0.05 level of Confidence. The Experimental Group was trained six days a week for 12 weeks excluding Sunday. After the 12th week, post-test scores were collected from both the Experimental Group and the Control Group and were analysed with ANCOVA. It was concluded that Blood Sugar decreased in the subjects due to the Yogic practices than the Control Group.