Objective: To compare the efficacy of Transversus abdominis plane block (TAP) and Quadratus lumborum block (QLB) for postoperative analgesia in abdominal surgeries. Background: Postoperative analgesia is vital after abdominal surgery as it facilitates early ambulation, recovery rate and overall patient satisfaction as good health outcomes. Many modalities are in use for post operative analgesia, but they come along with their own disadvantages. Regional block techniques like QLB and TAP are considered as safe techniques. Our study aims at use of TAP and QLB for postoperative analgesia following abdominal surgeries. Method: Prospective randomised study, patients undergoing abdominal surgery were randomised into 2 groups to receive ultrasound guided TAP (n=25) or QLB(n=25) bilaterally with 20ml 0.25% Bupivacaine plus 8mg Dexamethasone. The primary objective was to compare duration of analgesia. Secondary objectives was to compare the total number of rescue analgesia doses required with visual analogue scale (VAS) score up to 48 hours postoperatively. Data was compared using Pearson’s chi square test and unpaired t-test . Results: Duration of analgesia was higher in the QLB group than TAP group (mean±SD: 44.84±3.6 hours vs 24.64±1.55 hours) (P < 0.05). Number of rescue analgesia doses required in QLB group were significantly less than TAP group from 16 hours to 48 hours ( p <0.05) Conclusion: QLB showed significantly prolonged and effective analgesia than TAP due to its additional visceral nerves blockade action along with somatic nerves blockade.