Children are endlessly curious and want to explore, dismantle, and taste everything they find. Common causes of poisoning in children are in daily use in most households. Most often, poisoning in children occurs at age 1 to 2 years.\ Title of study: A pre-experimental study to evulatute the effectiveness of video assisted teaching programme on knowledge regarding prevention of household poisoning among mothers of preprimary school children at selected rural area of Pune. Material and Methods: the study adopted Quantitative approach with pre experimental, research design. It was carried out on 60 samples. The non-probability purposive sampling technique was used to select samples. Result: study result showed that the pre test means was 12.46 with the standard deviation of 2.7 and the post test mean was 19.2 with the standard deviation of 2.6. The mean difference of pre and post test is 5.4; standard error is 0.881. the ‘T’ value is 8.6 is significant at p <0.005 it indicates that the knowledge level of mother of are improved after video assisted teaching programme Conclusion: study concluded that the knowledge of the mothers improve after the intervention that mean video assisted programme was effective and improve knowledge regarding prevention of house hold poisoning in primary school children