Background: The demand for healthcare resources has been on the rise due to various factors such as aging populations, technological advancements, and emerging epidemics, leading to changes in healthcare management systems. Adequate nursing staffing is crucial for providing quality care in intensive care units (ICUs) and improving patient outcomes. Studies have shown that an increased nurse-to-patient ratio is associated with reduced mortality rates, while a decreased ratio can lead to increased workload, job dissatisfaction, and higher complication rates. It is essential to assess nursing workload and its impact on patient care quality and outcomes in ICUs. Objective: This review aims to evaluate the impact of nursing workload on patient outcomes in ICUs, assess the relationship between workload and nurse job satisfaction, identify factors contributing to high workload, explore strategies for workload management, and examine the association between workload and quality of care in ICUs. Evidence-based recommendations for optimizing nursing workload to enhance patient outcomes and nurse well-being will be provided. Conclusion: Nursing workload significantly influences patient outcomes in ICUs, with higher workload associated with increased complications and mortality rates. Adequate nurse staffing levels are crucial for improving patient safety and care quality. Effective workload management strategies, interdisciplinary collaboration, and leveraging technology are essential for optimizing nursing workload in ICUs. Further research on factors affecting nursing workload is necessary to enhance healthcare delivery in critical care settings. By implementing evidence-based recommendations and promoting teamwork, healthcare facilities can improve patient outcomes and nurse well-being in ICUs.