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ISSN 2063-5346
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EFFECT OF CHRONIC ALUMINUM CHLORIDE EXPOSURE ON HIPPOCAMPUS OF ADULT MALE ALBINO RATS

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Dina Ali Maher Abdel Dayem Ahmed, Amira Fathy Ahmed, Sara Mohammed Nagibabdel Hafez, Nashwa Fathy Gamal El-Tahawy, Seham Abdel Raouf Abdel Aleem
» doi: 10.31838/ecb/2023.12.5.347

Abstract

Background: Aluminum is a widely distributed metal in the environment. Also, it is categorized as a neurotoxin which has hazardous effects on the development of the brain Aim of the work: To study the effect of chronic administration of aluminum chloride on hippocampus in two different doses. Methods: twenty-four adult male rats were equally divided into three groups: group Ⅰ, Ⅱ and ⅠⅡ. Histological study was done using H&E staining. Results: Al Cl3-group showed variable histological changes in hippocampal features. Conclusion: Aluminum chloride in high dose (100mg/kg) had an obvious deleterious effect on histological structure of hippocampus.

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