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ISSN 2063-5346
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Effect Of 1% Alendronate Gel on IL-6 Levels in Non-Surgical Management of Chronic Periodontitis - A Randomized Clinical Trial & An Immunological Analysis

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Dr. Shradha , Dr. Sachit Anand Arora, Dr. Stuti Gupta, Dr. Ejya Sharma, Dr. Radhika Gupta
» doi: 10.48047/ecb/2023.12.8.140

Abstract

Alendronate (ALN), an aminobisphosphonate, inhibits osteoclastic activity, thus inhibiting bone resorption. Literature suggests that Alendronate reduces the levels of Interleukin-6 (IL-6) in osteoblastic cell cultures. So, the aim of the study was to evaluate the effect of 1% Alendronate Gel on of IL-6 levels in Gingival Crevicular Fluid (GCF), which was quantified by using ELISA and to compare and evaluate the effect of 1% Alendronate Gel on clinical parameters.

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