Educational neuroscience is an emerging discipline integrating teaching and learning with neuroscientific methods. In the recent past, undergraduate course curriculum is following outcome-based education (OBE) model where, course outcomes are to be attained by students and is a process of continuous assessment. Outcome based education is a theory that gives a systemic structure providing a scaffold for various teaching and learning activities. For an effective implementation of OBE, the process of learning needs to take inputs from a branch of neuroscience dealing with cognitive function. In this work, students concern regarding learning are articulated and then the same are addressed with inputs from neuroscience. Later, this is reinterpreted in the outcome-based education scenario. The present work also consolidates the relevance between levels of Bloom’s taxonomy and the educational neuroscience.