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ISSN 2063-5346
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DEVELOPMENT AND EVALUATION OF HERBAL CAPSULE FORMULATIONS FOR THERAPEUTIC TARGETS OF HYPERLIPIDEMIA

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Vikas B. Kandekar,Pankaj Kumar Sharma,Rahul K. Dumbre,Jaya Sharma
» doi: 10.31838/ecb/2023.12.3.133

Abstract

Hyperlipidemia is a term used to describe a group of genetic and acquired disorders for high lipid levels in the body. Several non-herbal medications are available to treat hyperlipidemia but they have several drawbacks. Herbal remedies have been made available for a variety of ailments by traditional systems. Hence, in the present study, three different herbal capsule formulations were prepared from the aqueous extract of Rasona, Tvak, Arjuna, Guduchi, and Mesasringa using a wet granulation technique and evaluated using different parameters. The dissolution profile of prepared capsules showed better drug release of 64.05%, 71.16%, and 76.14% in phosphate buffer (pH 6.8) for C1, C2, and C3, while 53.69%, 59.33%, and 62.08% drug release in 0.1N HCl within 2 hours. The presence of allicin and E-Ajoene in C1, Cinnamonaldehye, Eugenol, and Arjunic acid in C2, and Berberine, Dolichandroside A, and

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