The development of biologically active 3-hydroxyindoline derivatives have been widely explored as these molecules demonstrate a wide range of medicinal properties like antioxidant, anti-inflammatory and anticonvulsant. They have also been explored for their anti-microbial potential and have shown interesting results. While going through literature, it was observed that the synthetic and therapeutic potential of β-ionone based 3-hydroxyindoles have not been investigated. Already discussed in introduction, β-ionone derivatives have shown interesting antioxidant and anti-inflammatory properties. The aim of present research project is to design, synthesize and evaluate the biological potentials of β-ionone based 3-hydroxyindoles.