Drug research and delivery has recently emerged as one of the most dynamic, challenging, and expensive industrial industries. This labor-intensive and costly approach struggles with issues such limited bioavailability, toxicity, poor effectiveness, biocompatibility, side effects, rapid excretion, and degradability. The advantages of biocompatible nanomaterials over conventional drug forms include their extraordinary qualities of high invasion rate, gradual, controlled and targeted drug release, and easy accessibility to receptors. Regardless of all the significance, one of the central concerns with it is the poisonousness of the various nanoparticles used as drug delivery systems. Through cautious assessment of the disclosure and utilization of nanomaterials in working on the adequacy of both new and old drugs (like normal items) and specific finding through sickness marker molecules, the ongoing survey gives a refreshed outline of late advancements in the field of nanomedicines and nano based drug delivery systems. The benefits and impediments of utilizing nanomedicines for the remedial delivery of drugs from manufactured or regular sources are likewise covered. Additionally, we have remembered subtleties for the turns of events and points of view in the field of nanomedicine