Paraquat (PQ) is known to induce oxidative stress (OS), which causes damage to the cell membrane, DNA, lipids, and proteins. In the present study, we analyzed the degenerative effect of PQ-induced OS and the ameliorative effect of Aloe vera gel (AVG) on egg morphometry in Drosophila melanogaster (Dm). Flies were sorted into control (CTR), PQ-treated, and AVG+PQ co-treated. The control group was fed on Standard Drosophila Medium (SDM). The AVG- supplemented group was fed on SDM and Aloe vera gel (5mL/L). PQ-treated and AVG+PQ-treated groups were exposed to an 18mM/L concentration of PQ for 8 hours and were allowed to recover from PQ stress by feeding on their respective food for 48 hours. The eggs laid by mated females were analyzed morphometrically under a stereo-zoom microscope. A significant degenerative effect was observed for the eggs of Drosophila flies exposed to PQ without Aloe vera gel supplementation. In comparison, a substantial reduction in egg degeneration was observed where flies were supplemented with Aloe vera gel and PQ exposure. The result of the present study showed the degenerative effect of PQ and the ameliorative effect of AVG in Dm