Orchids are often admired for their aesthetic appeal, but they also have medicinal value. Orchids are highly prized for their medicinal properties due to the discovery of numerous phytochemicals, including alkaloids, flavonoids, and glycosides. Dendrobium macraei is an important orchid in Ayurveda since it is thought to be where Jivanti originates. The plant can be used as an expectorant, aphrodisiac, tonic, and in cases of heat exhaustion as it has a cooling effect. Asthma, bronchitis, "tridosha," throat issues, fevers, burning sensations, biliousness and disorders of the eye and blood are all treatable thanks to its medicinal characteristics. Extensive research was done on a variety of articles from different databases, and during this time, a number of articles and manuscripts were also deleted due to the lack of data on the species of Dendrobium macraei that was required for the construction of this document. Not only orchids are prized as ornaments, but they are also employed in herbal medicine. Seldom are the species utilised for various types of activity. To extract and identify the active compounds, as well as the mechanisms and modes of action that would serve as a source of communal knowledge on this plant from future perspectives, more research is required to examine the traditional usage of this plant scientifically. Dendrobium macraei contains phenolic compounds and flavonoids, it seems to be a potential candidate for enhancing memory, as a potent anti-inflammator and acts as a free radical scavenger. However, more research is required to fully explore the potential of Dendrobium macraei in treating a variety of ailments based on data from the literature study and traditional applications.