Providing patients with suitable drugs in the right amounts and for appropriate use during patient transfers is the essential function of medication reconciliation in healthcare. This investigation conducts a critical assessment of medication reconciliation processes led by nurses, embracing the weighing of their effectiveness, performance, and impact on the provision of continued care. The review provides a methodology of the published literature, including identification of gaps, theories, and methods that are currently being used and explored. This research paper is an in-depth and specific examination of research methodology, results, and findings to see the impacts of bedside nurses being effective leaders in terms of patient safety and continuity of care.