Introduction: Staple line leakage and bleeding are major complications that occur after sleeve gastrectomy. There was no agreement on whether a reinforcement approach should be routinely performed. Aim: The goal of this randomized controlled experiment was to examine the performance of staple line reinforcement, using V-Lock suture for the prevention of surgical complications after LSG. Patients and Methods: 90 cases who qualified for laparoscopic sleeve gastrectomy participated in this prospective, randomized, double-blind, controlled clinical research. Cases were divided randomly into two equal groups receiving staple line oversewing using V-Lock suture, compared to no staple line reinforcement. The incidence of complications following surgery was measured and contrasted among the 2 groups. Results: Postoperative bleeding was significantly more prevalent in the non-reinforced group contrasted with the V-Lock suture group (11 vs. 2 %, p=0.029). Moderate to severe bleeding was reported in one case in the non-reinforced group, which required urgent exploration. This study reported a statistically significant higher prevalence in the non-reinforced versus the V-Lock reinforced group (4.4 Vs 0 %, p= 0.001). Discussion and Conclusion: The findings of our investigation revealed that staple line oversewing through a V-Lock suture can considerably minimize postoperative staple line leakage and bleeding. Total time spent in the hospital was more prolonged in the no reinforcement group. Additional high-quality, large-sample RCTs are required to validate the study's future findings.