The work aimed to compare the role of Brocolli,folic acid or ferrous sulfate in treatment of anemia caused by lead acetate.52 female rabbits were divided into 5 randomized groups::1st group (control), 2nd ,3rd ,4th,and 5th groups were received lead acetate10 mg/kg.Bw/daily for 4weeks,3rd,4rd,5rdgroups also treated as following with folic acid, ferrous sulfate and alcoholic extract of the Brassica oleracea,blood samples were taken to calculate blood paramters.The results recorded a decrease in level of RBCs indices, PCV ,PPOX, iron and ferritin after administration of lead and increase in bilirubin concentration and TIBC. From other side after treatment by extraction plant, folic and iron the results seen revealed increase in erythrocyte indices,PCV,PPOX with a decrease in mean of bilirubin and elevated in value of iron,ferritin with decrease in TIBC. These results support the hypothesis that brocoli excrete beneficial effect in treating anemia and lessen effects on the hematological system.