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ISSN 2063-5346
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Clinical Profile of Rhino-Orbital-Cerebral Mucormycosis in Post-Covid Patients

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Dr. Ajit Lokare, Dr. Milind Samangadkar, Dr Ganesh Borewad
» doi: 10.48047/ecb/2023.12.7.268

Abstract

During the Covid-19 pandemic, several complications were being reported in patients who have recovered post-covid. One such lethal complication being reported in patients who had underwent treatment for Covid 19 infection in India in recent times, is a fungal disease called Mucormycosis or the black fungus. The aim of this retrospective observational study is to find out the clinical presentation, diagnostic nasal endoscopy findings and involvement on MRI scanning in the patients of post covid mucormycosis at CPR hospital Kolhapur from July 2021 to October 2021. Objective To study different clinical features of Post covid rhino-orbital-cerebral mucormycosis. To study diagnostic findings of Post covid rhino-orbital-cerebral mucormycosis patients and to study involvement on MRI in patients with Post covid rhino-orbital-cerebral mucormycosis. Materials and methods This is retrospective observational study and will be carried out in tertiary care center in Western Maharashtra from 1 July 2021 to 31 October 2021. Study population includes post-covid patients presenting with symptoms of rhino orbital-cerebral mucormycosis. Results A total of 229 patients of post covid 19 mucormycosis patients were included in the study. Out of 229 patients , ptosis was seen in 77 patients (32.77%), periorbital swelling in 73 patients (31.06%), ophthalmoplegia in 43 patients (18.30%), proptosis in 45 patients (19.15%), decreased vision in 56 patients (23.83%), palatal ulcer in 46 patients (19.57%), loosening of maxillary teeth in 25 patients (10.64%), toothache in 21 patients (8.94%), orbital pain in 38 patients (16.17%), headache in 51 patients (21.70), facial numbness in 14 patients (5.96%), facial pain with swelling in 40 patients (17.02), discoloured nasal discharge in 48 patients (20.43%) and nasal obstruction in 16 patient (6.81%). On diagnostic nasal endoscopy (DNE) out of 229 patients 151 patients (64.26%) had blackish crusting and 50 patients (21.28%) had mucopurulent discharge. On MRI involvement, out of 229 patients 229 patienst (100%) had sinus involvement, 122 patients (53.27%) had eye involvement, 9 patients (0.04%) had brain involvement, 13 patients (0.056%) had oral cavity involvement Conclusion Patients should be made aware of strict glycemic control and limited use of corticosteroids. Patients should seek immediate medical attention if develops headache, pain, facial swelling, diminution of vision so that timely medical action may be taken for ensuring survival. Surgical debridement of necrotic tissue is cornerstone of treatment which also provides sample for immediate fungal microscopy by KOH wet mount and Giemsa stain to provide quick possible diagnosis for timely management of the patients

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