A kidney stone, also known as a renal calculus (from the Latin rēnēs, "kidneys" and calculus, "pebble") is a solid concretion or crystal aggregation formed in the kidneys from dietary minerals in the urine. It was found that mandelic acid is a good inhibitor for calcium carbonate, calcium phosphate and calcium oxalate mineralization and on increasing the strength of inhibitor solution its inhibition efficiency is increased. Mandelic acid is a more efficient inhibitor for calcium carbonate salt comparing to calcium phosphate and calcium oxalate. Simultaneous dynamic model was proved to be more efficient than reservoir dynamic model. Karaunda extract is a good inhibitor for the dissolution of kidney stone. The percentage of dissolution of powder stone is more than the whole renal stone.