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ISSN 2063-5346
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CARBON NANOTUBES โ€“ AN EMERGING THERAGNOSTIC DRUG DELIVERY NANO-CARRIER FOR TUBERCULOSIS

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Pavithra Selvan, Nalini Jayanthi Nagesh,Pugazhendhi S, Shaz Assain
ยป doi: 10.48047/ecb/2023.12.4.218

Abstract

Globally, tuberculosis (TB) is the main reason for fatality and it is a communicable illness,which significantly contributes to ill health conditions. In advance of the pandemic coronavirus (COVID-19), the prevalent infectious disease to cause mortality was TB, over HIV/AIDS. A recently developed category of materials known as carbon nanomaterials (CNMs) has been extensively employed with various applications on the therapeutic side, including cancer treatment, drug delivery, tissue engineering, and diagnostics.Carbon nanotubes (CNTs) is an ideal material for the detection and suppression of M. tuberculosis. These nanomaterials have a high photothermal conversion efficiency, the capability to generate reactive oxygen species (ROS), and are resistant to the majority of acids and bases.They have been found to be used in diagnostic and drug/gene delivery methods for fighting several infectious diseases, including tuberculosis. Properties, Drug loading, and delivery mechanisms of CNTs used in the theragnostic approach of TB are discussed in this review. The utilization of nanomaterials as anti-TB drug delivery systems seems to be an intriguing strategy to enhance TB therapy by lowering time and toxicity.

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