The field of bone grafting has made great strides. Newer materials and techniques to enhance and improve the mechanical resistance, durability and compatibility are currently being developed and studied. As described in the literature over the last few years, the qualitative characteristics of bone graft scaffolds are critical for cell and nutrient infiltration; and that it greatly enhances the post operative compatibility. Currently, most researchers are studying the introduction of various biologically safe and acceptable materials and their use to improve the mechanical integrity of grafts. This article presents review of advanced bone graft materials and their contribution in managing bone defects.