As a green chemistry approach for synthesizing organic molecules, the use of microwave to expose reactants with or without solvents is explored here. Analytical, inorganic, and organic chemists all employ Schiff bases (SBs) in their work. The need for SB synthesis is further emphasized by a broad variety of pharmacological and biological functions, including analgesic, antiproliferative, antiviral, anti-inflammatory, antibacterial, antipyretic, and antifungal activities. In a variety of processes particularly when there is moisture present, several Schiff base complexes have good catalytic activity. The study of these compounds' coordination behavior has significantly increased because of the impact that specific metals have on their biological properties and its inherent chemical significance as multidentate ligands. The overview of the synthesis of SBs and its metal compounds Schiff bases and its metal complexes using various green methods and ionic liquid techniques is discussed here. Examples of the most promising applicable SBs and its metal compounds from many fields are included in this overview.