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ISSN 2063-5346
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ASSOCIATION OF ADIPOSITY INDICES AND SPIROMETRY PARAMETERS AMONG OVERWEIGHT AND OBESE ADULTS IN THE COMMUNITY: A CROSS-SECTIONAL COMMUNITY-BASED STUDY PROTOCOL

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Balamurugan Janakiraman, Parthasarathy Ranganathan, Koushik kumar Nandhagopal, Janani Ravi, Hariharasudhan Ravichandran, Mohammad Sidiq Nalini Devarajan, Sureka Varalakshmi
» doi: 10.31838/ecb/2023.12.s2.220

Abstract

Background: The prevalence of adiposity among children and adults in India is a long standing epidemic. The adverse effects of excessive fat accumulation is extensively reported for many non-communicable diseases in India. Yet, the empirical evidence of pulmonary impairment among non-smoking overweight and/or obese adults is overseen. Objectives: This study seeks to investigate the proportional relation-ship between the pulmonary function parameters and degree of adiposity indices among non-smoking community dwelling adults living in Chennai city. Further, the burden of pulmonary impairment, and gender difference will be established. Methods: The research will be conducted in three phases: the initial phase will be conduction of scoping review to map the evidence of obesity distribution in South India, the second phase will be conducting a cross-sectional study to determine the burden of pulmonary impairment among obese adults and assess the relation-ship between the lung function parameters and degree of obesity, the final phase is to develop a home-based intervention strategy and delivery system to improve or restore the pulmonary function among obese adults with lung impairment. This protocol explains the proposed template to conduct a community-based cross-sectional study among the selected households from the selected division of the Chennai city. The adult participants with BMI > 25 kg/m2 will be selected based on the systematic random sampling method from the selected households. Data collection tool consist of; socio-demographic data, physical measurements (BMI, AC, WHtR, and WHR,) and pulmonary parameters using spirometry. Ethics and dissemination: This protocol was approved by the Institutional human ethics committee (DHR reg no: EC/New/INST/2021/2220), Meenakshi Medical College Hospital and Research Institute (MMCHRI), and approval for conduction was obtained (Ref no MMCH& RI IEC/Faculty/01June/2022) and prospectively registered in the Clinical Trial Registry of India (CTRI/2022/04/042313). The results will be presented in the Chennai regional, national, international conferences and the findings will be published in peer-reviewed journals. Results: The findings will be described using mean, frequency distributions, SD, and percentages with 95% CI adjusted for age, the distributions of socio-demographic characteristics, anthropometric measures and cardiometabolic of the study population by cross tabulation and independent t-test across gender. Pearson’s chi-square will be used to evaluate the difference between a categorical variable and age-adjusted. One-way ANOVA will be used to compare continuous variables. Pearson’s correlation test will be done to measure the association between anthropometric measures (BMI, WC, WHtR & WHR), age, and spirometry parameters (Fev1, FVC, Fev1/FVC, PEF). Age controlled bivariate analyses will be conducted with the dependent variables and independent variables then will be taken to multivariate analysis model based on assumptions. Statistical significance wiil be at a p-value of 0.05. Discussion: This study will provide an insight into the overall relationship and discrete associations between the anthropometric indices and spirometry parameter among the non-smoking adults in Chennai.

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