Y-Balance test (YBT) one of the most commonly used dynamic test that was found to be able to predict non-contact injuries. However, there is a lack of understanding of the association between knee muscle strength and YBT. OBJECTIVES: To investigate the association between isometric knee strength and YBT performance in male and female athletic students. METHODS: Thirty-six healthy athletic students (17 women, 19 men), aged 22±2 years, voluntarily participated in this study. Peak knee flexor and extensor torques were measured using the Biodex Isokinetic System 4 Pro. The YBT scores in the anterior, posteromedial, and posterolateral directions were measured. The normalized knee flexor/extensor peak torque and YBT scores were used in the analysis. Pearson’s correlation was used to investigate the association between knee flexor/extensor peak torque and the YBT scores in the three reach directions. RESULTS: There was a significant positive association between YBT performance and knee flexor strength in all three reach directions (anterior r=.388, p=.019; posteromedial r=.37, p=.024; and posterolateral r=.42, p=.011) but not knee extensor strength (p>.05). CONCLUSIONS: YBT performance correlated with knee flexor but not with knee extensor strength. This information may aid clinicians and researchers in developing injury prevention programs.