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ISSN 2063-5346
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Assessment of Pharmacokinetic parameters and antihypertensive activity of prepared sildenafil transdermal patches

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Dr. Rupal Dubeya*, Umadoss Pothuvanb , Dr. Arun Kumar Pandeyc
» doi: 10.48047/ecb/2023.12.8.724

Abstract

The aim of present study was to prepare and evaluate sildenafil transdermal patches for antihypertensive activity, which can be beneficial and convenient for the children who have been connected with Pediatric Pulmonary arterial hypertension and In this project, we investigated the antihypertensive effect of the formulated patches in deoxycorticosterone acetate (DOCA)–salt rat model. Antihypertensive activity was evaluated in sildenafil patches for 4 weeks in DOCA treated rats.

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