Practically every area of science and technology, including healthcare, is currently undergoing a huge paradigm shift as a result of artificial intelligence (AI). In order to develop AI-based healthcare systes, Therefore, this study aimed to study aimed to explore the artificial intelligence and its applications in nursing healthcare and laboratory in Saudi arabia, The descriptive study was used, a theorethical framework based on UTAUT is proposed in this study whoch theorizes that four constructs play a significant role as direct determinants of user acceptance and usage behaviour: performance expectancy, effort expectancy, social influence, A quantitative study is conducted using questionnaire to artificial intelligence and its applications in nursing healthcare centers and laboratory in Saudi arabia, the results of this study may be provide the developers of AI-based healthcare systems in Saudi Arabia in Saudi Arabia.