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BIOCHEMISTRY OF FASTING – A REVIEW ON METABOLIC SWITCH AND AUTOPHAGY.
Volume - 13 | Issue-1
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ONE-POT ENVIRONMENT FRIENDLY SYNTHESIS OF IMINE DERIVATIVE OF FURFURAL AND ASSESSMENT OF ITS ANTIOXIDANT AND ANTIBACTERIAL POTENTIAL
Volume - 13 | Issue-1
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MODELING AND ANALYSIS OF MEDIA INFLUENCE OF INFORMATION DIFFUSION ON THE SPREAD OF CORONA VIRUS PANDEMIC DISEASE (COVID-19)
Volume - 13 | Issue-1
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INCIDENCE OF HISTOPATHOLOGICAL FINDINGS IN APPENDECTOMY SPECIMENS IN A TERTIARY CARE HOSPITAL IN TWO-YEAR TIME
Volume - 13 | Issue-1
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SEVERITY OF URINARY TRACT INFECTION SYMPTOMS AND THE ANTIBIOTIC RESISTANCE IN A TERTIARY CARE CENTRE IN PAKISTAN
Volume - 13 | Issue-1
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION BY SIMULTANEOUS ESTIMATION OF MONTELUKAST SODIUM AND BILASTINE BY UV SPECTROPHOTOMETRY
Main Article Content
Abstract
A simple, sensitive, specific UV Spectrophotometer method was developed and validated by simultaneous estimation of Montelukast Sodium and Bilastine. The optimum conditions were obtained, UV Spectra was achieved on 20/06/2021. The wavelength maxima of Bilastine and Montelukast Sodium were found to be 282 and 287 respectively. The linearity for this method was found to be in the range of 20-1 mcg and 10-0.5mcg for Bilastine and montelukast sodium respectively. The method showed highly sensitive with reproducibility in results. The calibration curve was drawn between absorption and concentration. The method showed the correlation coefficient(R) as 0.966 and 0.967 of Bilastine and Montelukast Sodium respectively. The regression equation was y= 0.159x-0.213 and y=0.094x-0.121 for Bilastine and Montelukast Sodium respectively. The proposed method may be suitable for the analytical method validation in bulk of Bilastine and Montelukast Sodium (2:1).
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