Diabetes mellitus is a one of the disastrous chronic disorder in the endocrine system which is major cause of mortality globally.Many disorders develop including hyperinsulinemia, hypertension, hyperlipidemia and atherosclerosis associated with diabetes mellitus.Semi-hydrolyzed guar gum possesses hypoglycemic potential. A total of 50 subjects fulfilling inclusion and exclusion criteria as listed below were enrolled to identify the antidiabetic potential of guar gum as an add on therapy.significant difference between first and last screening visit of fasting blood sugar level and post prandial blood sugar level in both control (P= 0.00) and treatment groups(P=0.00) and also a significant difference between first and last screening visit of HbA1C (glycatedhaemoglobin) in both control (P=0.00) and treatment groups (P= 0.00). Subjects who were treated with combination of Metformin + Glimiperide + Rosuvastatin and Guar powder as add on therapy comparatively better clinical outcome in terms of glycaemia control, lipid lowering action. This study also suggests the rationale for using guar as add on therapy for diabetes mellitus.