Alzheimer’s disease is defined as the degenerative disease of the brain resulting in progressive memory loss, impaired thinking, deterioration, and changes in personality and mood. It includes deterioration of language, comprehension, memory, and thinking and learning capability. The term Alzheimer was first coined by a German physician, Alios Alzheimer, in 1915,The present study title:“A study to asses the effectiveness of structure teaching programme on knowledge regarding Alzhimers disease among adults from selected area of Pune city.” Material and Methods: In present study, researcher adopted Quasi experimental design one group pretest, post test design. It was carried out on 60 samples. The Non-probability Convenient sampling method was used to data was collected using demographic profile and clinical profile. Data analysis was done mainly using descriptive statistics. Result: Result revealed mean score of pretest is 7.75 with sd of 3.5 which is less than post test mean 14.95 with 2.18 SD and calculated value of paired t test was 17.35 with p value 0.00001. so p value 0.00001 is less than 0.05 level of significant which means null hypothesis rejected and there is effect of structure teaching programme. Conclusion : After administration 31.7% participants were having Average Knowledge and 68.33% were having Good knowledge one was having poor knowledge .