Amongst the massive world medicines, anti-microbial agents (antibiotics) are one of the widely used and misused drugs available to medical profession. Once upon a time they were called as the magic bullets for the great contribution in caring an infection, but recently these bullets also back fire in way of causing resistance, decreasing their effectiveness and causing side effect. through the centre for disease control and prevention has taken flaring at a rampant rate due to over prescribing of these drugs. This over prescribing is driven largely by patient demand, time pressure on clinicians and diagnostic uncertainly fuelling on ever increasing need for newer drugs.