A persistent tympanic membrane perforation increases the patient risk of developing recurrent acute otitis media or chronic middle ear disease, These conditions are frequently associated with an unpleasant otorrhea, Type I Tympanoplasty is a surgical procedure that closes a simple perforated tympanic membrane. Aims: The aim of this procedure is to create an intact tympanic membrane, forming a dry ear and no further need to protect the ear from water after complete healing. Materials and methods: This study included 50 patients selected from the ENT out-patient clinic of Mediciti Institute of Medical Sciences, presenting with COM Inactive mucosal type divided into 2 groups with 25 patients in each group. All of them underwent type one underlay tympanoplasty were prospectively reviewed. Group 1 patients received fascia graft with PRP. Group 2 patients received fascia graft without PRP. Post -operative evaluation as Clinical follow-up, graft taking, perforation, retraction, lateralization or blunting, for three months post-operatively. Audiological follow-up by pure tone audiometry at three months. Results: In Group A 21 patients (84%) had healed the tympanic membrane perforation, 4 patients (16 %) had residual tympanic membrane perforation at 3 months followup. No other complications such as lateralization or retraction were noted post operatively. In Group B 17 patients (68%) had healed tympanic membrane perforation , 8 patients (32%) had residual tympanic membrane perforation at 3 months follow up postoperatively. No other complications such as lateralization or retraction were noted post-operatively. Conclusions: Our study concludes that Platelet rich plasma is a cheap and cost effective platelet concentrate with enriched growth factors, topical autologous PRP application during Type I Tympanoplasty is safe and highly efficient and successful with no reported complication.