In the fight against dengue, various strategic measures have been outlined by World Health Organization needed to be improved, including the management and diagnosis of dengue cases, integrated surveillance and emergency preparedness, sustainable vector controls, implementation of future vaccine, and basic operational research. To control the vector of dengue in Malaysia, various dengue prevention techniques have been introduced to combat dengue for the sake of environmental sustainability. However, stakeholder attitudes towards these techniques must be considered to ensure their acceptance. Therefore, this study proposes a conceptual framework to identify predictive factors that are expected to influence stakeholders' attitudes towards dengue prevention techniques in Malaysia. The proposed framework is beneficial for enhancing the awareness of stakeholders of the acceptance of any techniques to combat dengue. The framework also can be a guideline and allows for ongoing research to be conducted to ensure the best techniques. In fact, this framework can be used in any study that requires an assessment of stakeholders' acceptance of any current science and technology product.