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ISSN 2063-5346
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A COMPREHENSIVE ASSESSMENT OF ANALYTICAL AND BIOANALYTICAL TECHNIQUES FOR QUANTIFYING THE ALPHA ADRENERGIC AGONIST PHENYLEPHRINE

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Shubhasree K, Manikandan K, Kamesh K
» doi: 10.31838/ecb/2023.12.s2.134

Abstract

Nasal congestion lead to tissue hypertrophy and blood vessel occlusion. Congestion might trigger a "runny nose." Blockage or impaired sensory processing generate congestion. Mucosal inflammation exacerbate congestion and allergy symptoms.(Seidel & Faubel, 1999) Inflammation, triggered by so many physiologically active agents and cell types, could lead to congestion and difficulty in breathing (including histamine, TNF -, interleukins, and cell adhesion molecules). Inflammation can damage nasal congestion, venous engorgement, and tissue swelling/edema . Rhinosinusitis affects tens of millions of Americans annually and costs US employers $6 billion in health care costs. Nasal congestion's social and economic burden is high. Adrenergic (phenylephrine) and intranasal corticosteroids are prescribed (beclomethasone dipropionate).

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