The current study focused on FT-IR spectroscopic method development and validation for simultaneous estimation of aceclofenac (ACF) and pregabalin (PGL) in combined tablet dosage form.Aceclofenac and pregabalin are used in combination for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis and adjunctive treatment of partial seizure, epilepsy, fibromyalgia, neuropathin pain drug. Literature survey revealed that no method is reported on FTIR method for the simultaneous estimation of the aceclofenac & pregabalin in bulk and combined pharmaceutical dosage form.The method is validated with respect to linearity, precision, accuracy, robustness, ruggedness and system suitability parameters as per ICH guidelines. The developed method was applied to forced degradation studies successfully to verify the utility of the established procedure.