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ISSN 2063-5346
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TO DETERMINE ASSOCIATION BETWEEN GLYCEMIC CONTROL AND LIPID PROFILE IN LEAN AND OBESE TYPE 2 DIABETES MELLITUS PATIENTS BASED ON BMI.

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Dr Nikhil Dilip Patil, Dr. Sanjay Thorat, Dr. Dilip Patil, Dr. Makarand Mane, Dr.Pankaj Pawar, Dr Aditya Bahekar
» doi: 10.31838/ecb/2023.12.s2.022

Abstract

The prevalence rate of diabetes is increasing throughout the world mostly in the developing countries. WHO reported 32 million diabetes affected Indians in the year 2000. The International Diabetic Federation estimated that the number would rise to 69.9 million by 2025 and 80 million by 2030.Dyslipidemia, especially high LDLC, is common in diabetes mellitus and strongly associated with poor glycemic control. Aim:To find out if there is significant difference in lipid profile of lean and obese type 2 diabetes mellitus patients. Material and methods:A hospital based cross sectional study was carried out at a tertiary care hospital, in medicine outpatient department (OPD) and ward under Medicine department of KIMSDU and having Diabetes mellitus type 2 conducted over a period of 18 months from November 2020 to March 2022. Total 100 cases were studied. Informed and written consent was taken from all patients and were explained about the same. All patients were subjected to detailed history, physical examination. Patients were divided into two groups Lean and Obese patients according to their BMI, 40 as lean and 40 as obese. All data was collected and compiled in micro-soft excel. Quantitative data was presented using mean and qualitative data by proportion and percentage. Analysis was done by applying appropriate analytical test. Results: Out of total 100 cases 17% were lean type, 52% non-obese and 31% obese.Hypercholesterolemia was seen in 10% in lean, 25% in non-obese and 25% in obese group. But hypertriglyceridemia was more among lean people as compared to non-obese and obese group and LDL was more in obese group. Conclusion: Present study revealed that lean T2DM had higher tendency of microvascular complications than obese T2DM. Lean T2DM is definitely different subset of population of T2DM with clinical characteristic different from those of other subtypes of T2DM non-obese and obese. Lean group of patients with T2DM should be evaluated thoroughly and treated accordingly to avoid further development of microvascular complications considering the inadequacy of BMI in distinguishing leanness, future studies should investigate the complex interaction between body composition, amount and distribution of adipose tissue and physical functioning in determining the development of lean diabetes.

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