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ISSN 2063-5346
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THE TRENDS OF HEMOGLOBINOPATHIES IN THE MITHILA REGION OF BIHAR

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Shadman Moiz , Ajay Nath Jha, Ajit Kumar Chaudhary , Mohammad Saquib Ashraf
» doi: 10.31838/ecb/2023.12.s3.370

Abstract

Hemoglobinopathies are caused by mutations in the globin genes that encode for the protein that synthesizes the hemoglobin chains, which is one of the most commonly occurring monogenic diseases in the world. In thalassemia, hemoglobin production is reduced, or abnormal hemoglobins are formed, resulting in a wide range of disorders. Globally, hemoglobinopathies have become increasingly common over the last few decades. Due to the growing burden on healthcare delivery systems, it is especially important for developing countries like India as well as the Indian states. The overall prevalence of  thalassemia carriers in India is 3-4%, according to the 2011 Census of India. While the demographic situation in Bihar has improved in recent years, the state's socioeconomic status remains low, and the incidence of a number of diseases has remained high despite these improvements. In our study, we found that hemoglobinopathies are a major problem in this region and we need to take precautionary measures to ensure the safety of our Mithila people, who have limited resources. There is no existing study in the Mithila region of Bihar State that uses standardized guidelines and methodology to screen for hemoglobinopathies, and this is the first study to do so at the Thalassemia clinic at the DMCH.

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