Introduction: An individual's cancer trajectory has been described as a 'living-dying' experience in which s/he confronts the awful incompatibilities between life and death and seeks to keep control and normalize daily activities. Perceptions of the duration, course, and impact of a disease affect the recovery and management of the disease. Aim: The purpose of this study was to explore the psychological trajectory of cancer patients in India interpretive phenomenological analysis (IPA). Method and Materials: Eleven participants ranging in age from 19 to 80 years old (five male and six female) were enrolled in the study. A semi-structured interview schedule was used to acquire the data. Results: The IPA produced four superordinate and eight subordinate themes. Encounter with medical care (Empathy and communication with doctor and Opinions about treatment), After-effects of sickness (Dissatisfaction with body and Emotions of uncertainty- Democles syndrome), and finally, Hopelessness/Hopefulness. Based on these superordinate and subthemes, the psychological trajectory of cancer patients in India was split into three phases: the initial, shock and transition phase, the second, encounter, sustenance and recovery phase, and the third, survivorship phase. Implication of the study: Patients, physicians, and lawmakers must acknowledge that the psychological requirements of cancer patients cannot be ignored, as it not only affects their quality of life and survival, but also the economic burden arising from cancer occurrence and recurrence.