In the realm of the environment, a great deal of research has been done on the poisonous and damaging impacts of heavy metals including arsenic, mercury, and others. Due to environmental pollution and the bioaccumulation of certain heavy metals in the food chain, they adversely impact human health despite their presence in low concentrations (10 ppm). Recent research studies suggest that exposure to arsenic during various life stages leads to gut microbial dysbiosis and is linked to immune dysfunction, altered lipid metabolism, and neurobehavioral damage. Therefore, it is important to detect, analyze and remove it from the environment to reduce its direct effect on human health.